Selected Publications

“Look to the genome to rebuild healthcare” -Leroy Hood, Institute for Systems Biology

• Niculescu AB, Le-Niculescu H. Precision medicine in psychiatry: biomarkers to the forefront.   Neuropsychopharmacology. 2022  Jan 47(1):422-423. doi: 10.1038/s41386-021-01183-3. PMID: 34584209
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• Le-Niculescu H, Roseberry K, Gill SS, Levey DF, Phalen PL, Mullen J, Williams A, Bhairo S, Voegtline T, Davis H, Shekhar A, Kurian SM, Niculescu AB. Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs.  Molecular Psychiatry. 2021 Jul 26(7): 2776-2804. doi: 10.1038/s41380-021-01061-w. Epub Apr 8 2021 PMID: 33828235
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• Niculescu AB, Le-Niculescu H, Roseberry K, Wang S, Hart J, Kaur A, Robertson H, Jones T, Strasburger A, Williams A, Kurian SM, Lamb B, Shekhar A, Lahiri DK, Saykin AJ. Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs.  Molecular Psychiatry. 2020 Aug; 25(8):1651-1672. doi: 10.1038/s41380-019-0602-2. Epub Dec 12 2019 PMID: 31792364.
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• Niculescu AB, Le-Niculescu H, Convergence of recent GWAS data for suicidality with previous blood biomarkers: independent reproducibility using independent methodologies in independent cohorts.  Molecular Psychiatry. 2020 Jan; 25(1): 19-21. doi: 10.1038/s41380-019-0465-6. Epub August 5 2019. PMID: 31383925
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• Supplementary Information -Complete Data

• Le-Niculescu H, Roseberry K, Levey DF, Rogers J, Kosary K, Prabha S, Jones T, Judd S, McCormick MA, Wessel AR, Williams A, Phalen PL, Mamdani F, Sequeira A, Kurian SM, Niculescu AB. Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs.  Molecular Psychiatry. 2020 May; 25(5): 918-938. doi: 10.1038/s41380-019-0370-z. Epub March 12 2019  PMID: 30862937
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  • Supplementary Information -Figure S1-S2 and Tables S2-S4.docx
  • Supplementary Information-Detailed Demographics Table S1.docx
  • GEO (GSE125216)

• Niculescu AB, Le-Niculescu H, Levey DF, Roseberry K, Soe KC, Rogers J, Khan F, Jones T, Judd S, McCormick MA, Wessel AR, Wiliams A, Kurian SM, White FA. Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs.,  Molecular Psychiatry. 2019  Apr; 24(4): 501-522. doi: 10.1038/s41380-018-0345-5. Epub Feb 12 2019 PMID: 30755720
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  • Supplementary Information -Figure S1 and Tables S2-S5.docx
  • Supplementary Information-Detailed Demographics Table S1.docx
  • GEO (GSE127208)

• Brucker KM, Duggan C Roseberry K, Le-Niculescu H, *Niculescu AB,  *Kline JA. Assessing Risk of Future Suicidality in Emergency Department Patients,  Academic Emergency Medicine. 2019 Apr; 26(4): 376-383  2018 Oct 30. doi: 10.1111/acem.13562. Epub Oct 30 2018  PMID: 30375082

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  • Supplementary Information Tables S1-S3.docx
  • Supplementary Information -Complete Datasets and Analyses

   

• Niculescu AB, Le-Niculescu H, Levey DF, Phalen PL, Dainton HL, Roseberry K, Niculescu EM, Niezer JO, Williams A, Graham DL, Jones TJ, Venugopal V, Ballew A, Yard M, Gelbart T, Kurian SM, Shekhar A, Schork NJ, Sandusky GE, Salomon DR. Precision medicine for suicidality: from universality to subtypes and personalization. Molecular Psychiatry. 2017 Sep;22(9):1250-1273. doi: 10.1038/mp.2017.128. Epub Aug 2017 PMID: 28809398

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